Senior Analytical Biochemist (Mass Spectrometry)

Job Description

Senior Analytical Biochemist (Mass Spectrometry)

At Ingenza, we are a dynamic, passionate team of 50 scientists and innovators driven by a singular mission: turbocharging biological systems to solve the world’s biggest challenges. From life saving therapeutics to sustainable consumer products and industrial enzymes, we transform science into scalable, real world solutions for human health and the global environment. As a fast growing, value led SME, we combine scientific excellence with a genuinely supportive culture of integrity and collaboration.

Embedded within a vibrant, sociable team, you will lead by example from our brand new, state of the art facilities at the Edinburgh Technopole. Surrounded by nature trails, an on site café, and stunning views of the Pentland Hills, you’ll find the perfect balance of breakthrough science and a world class working environment. To thrive here, you will possess excellent multitasking skills and the agility to navigate a fast paced dynamic work environment.

Skills and Experience

In this position, you will step into a pivotal role at Ingenza as a Protein Characterisation and MS Specialist. You will combine high level technical expertise in protein and peptide mass spectrometry with project leadership, demonstrating a proactive initiative and outstanding teamwork skills to deliver key customer results in a timely and accurate manner. The successful candidate will have a proven ability to work closely with senior management, providing strategic technical updates, aligning analytical capabilities with commercial objectives and helping shape the long term scientific direction of our services.

Essential Qualifications

• A PhD or Masters in Analytical Chemistry, Chemistry, Biochemistry, or a closely aligned subject.
• For Master’s level candidates, a minimum of four years of dedicated industrial experience is essential.

Essential Technical & Professional Skills

• Advanced LC-MS Operation: Deep technical knowledge and hands on experience working with high resolution LC-MS instrumentation (e.g. Q-TOF-MS, TQ-MS) for protein and peptide analysis.
• Structural Characterisation: A fundamental understanding of how accurate mass and MS/MS workflows can be leveraged to resolve complex structural characterisation challenges.
• PTM & Glycan Profiling: Proven experience with post translational modification (PTM) analysis and N released glycan analysis workflows relevant to biotherapeutic regulatory filing requirements.
• Method Innovation: A track record of evaluating and developing novel methodologies or technological advancements to expand and upscale analytical capabilities with hands on experience in method validation aligned with regulatory expectations.
• Complex Data Interpretation: Rigorous experimental standard to interpret, analyse, and QC complex MS data at both the intact mass and peptide level.
• Instrumentation Custody: Confidence in the routine maintenance, calibration, and troubleshooting of high resolution analytical instrumentation.
• Software Proficiency: Proven expertise utilizing Agilent software (such as MassHunter and BioConfirm) and familiar with other online MS data processing tools for both macromolecule and small molecule analysis.
• Data Translation: Ability to distil complex analytical data into accessible, clear formats for non specialist stakeholders, constructing professional presentations to deliver insights to project teams and customers.
• Interdisciplinary Collaboration: Outstanding team skills, and proven ability to collaborate effectively across diverse scientific disciplines and functional departments (e.g., molecular biology, fermentation and downstream processing) to achieve critical project milestones and deadlines.
• Dynamic Delivery: Proven ability to multitask seamlessly across parallel projects, coping with short timelines and managing competing tasks without compromising accuracy or data integrity.
• Technical Writing: Expertise in scientific writing to generate comprehensive project reports, technical protocols, and SOPs within an industrial quality management framework.
• Biochemistry & Biocatalysis: Strong working knowledge of biochemistry, protein chemistry, and biocatalysis concepts to contextualise analytical data and enhance how we monitor enzyme performance and structural integrity.

Desirable Technical & Professional Skills

• Proposal Contribution: Experience in writing and contributing to project proposals, specifically outlining MS-based methodologies and identifying how they can be deployed effectively to secure new business or funding opportunities.
• Host System Exposure: Knowledge and hands on experience with different host systems, including mammalian (e.g. CHO/HEK293 cell culture) or multiple microbial hosts (e.g. coli, P. pastoris, B. subtilis).
• Orthogonal Protein Characterisation: Good knowledge of recombinant protein analysis and purification methods (e.g., SDS-PAGE, Western Blot, or chromatography using the ÄKTA system).
• Line Management: Previous line management or mentoring experience.
• BD & Promotional Content Generation: Ability to generate compelling, scientifically accurate content to support marketing and business development (BD) efforts, including creating promotional material for our company website, social media platforms, case studies and other outward facing commercial outlets.

Specifics

• Senior Analytical Biochemist (Mass Spectrometry)
• Closing date: Friday 7th of August 2026
• Location: Edinburgh Technopole, Milton Bridge, Midlothian
• Hours: 37.5 h, Monday – Friday
• Work pattern: Days
• Duration: Permanent
• Pension: Available
• Salary: Dependent on qualifications and experience

What We Offer

We provide a stunning work environment and a competitive benefits package designed to support your health, well being, and career growth:

• The Setting: Work from a brand-new facility featuring nature trails, free on site parking, an on site cafe and views of the Pentland Hills.
• Health & Wellbeing: BUPA level 1 health expenses cover, Unum health and wellbeing services and a nearby gym.
• Financial & Perks: Company pension scheme, performance based annual bonus, Perkbox membership and a cycle to work scheme.
• Culture: Flexible working hours, regular social events and paid for company nights out